The aim of the study was to identify and assess the epidemiology, prescription pattern and monitoring and control of diabetes in SCCL Main Hospital, Kothagudem. Patient data collection form was developed based on the essential details to be collected from the patient. Demographic information like name, age, sex, and locality were included. A Prospective study design of 100 adult (above 18 years of age both male & female) diabetic patients were conducted for a period of six months. The data was analyzed using Graph Pad Prism statistical software version 6.04 and SPSS statistical package version 22. Mean and standard deviation for continuous variables and percentage for categorical variables are reported relevant. In the study population of diabetes among males were 38% and among females were 62%. A gradual increase in the diabetes from 41-50 years onwards, with maximum diabetes of 36% was noticed between 51-60 years of age. The mean age male were 7.6(±6.2 SD) and female mean age were 10.33(±7.7SD). Most commonly prescribing pattern of anti diabetic drugs in monotherapy of anti-diabetic drug group was biguanide (33.33%), sulphonylureas (19.24%) Thiozolidinediones (0.64%) Dipeptidyl Peptidase 4 Inhibitor(0.64%) and Insulin (16.66%). In Dual therapy, 14.74% were Sulphonylurea + Biguanide and 14.74% were DPP4 + Biguanide. The over all prescribed monotherapy percentage 70.51% and dual therapy percentage 29.48%. Average number of drugs per prescription was 18.22%. Percentage of generic names drugs 10.69% were prescribed by generic name. Percentage of antibiotic drugs 3.35% were prescribed, percentage of injections 3.35% were prescribed and Percentage of drugs prescribed from WHO essential drugs list was 5.15%. This study depicts the use of varied normally prescribed anti-diabetic drugs. Among the Biguanide group Metformin use was found to be maximum and Glimepiride among the sulfonylurea group. Prescribing patterns got to be improved in accordance with WHO core indicators.