Malaria is a vector-borne disease transmitted by the bite of an infected female anopheles mosquito presents with varied clinical manifestations. Neurological manifestations include headaches, confusion, convulsions, hemiplegia, ataxia, cerebral palsy, cortical blindness, and Guillain-Barre syndrome (GBS). We are presenting a case report of acute cerebellar Syndrome in a 45 year old male patient who presented with fever and positive for Plasmodium falciparum malaria.