Drug utilization research is increasing and it is being carried out in health setups, in order to study the use of drugs in a hospital as well as in the community. This has immense medical social and economic consequences of the country. The present aim of the study on drug utilization of cardiac unit in acute myocardial infarction of hospitalized patients, this is a prospective study conducted at MGM Hospital (Government), Warangal, Andhra Pradesh, India. The largest medical care centre in Northern Telangana region. Practitioner at this centre was a combination of specialization and general physician. Data were collected for the period of 9 months (1st February-1st November 2011). All in-patients from cardiology ward of MI were screened. The results of the present study reveals that, 61 (100%) received anticoagulants, anti-anginals and antihypertensive drugs 60 (98.4%), 54 (88.5%) lipid lowering drugs, 24 (39.34%) thrombolytic, and 14 (22.9%) inotropic agents. Our article highlighted that Patient education and understanding of the nature and complication of treatment on part of clinical pharmacist can avert many of this complication. It is the responsibility of government to adopt the clinical pharmacy service providing employment for clinical pharmacist at all government and private hospitals in developing countries i.e., South East Asian Countries (SEAC), so that the clinical pharmacist can educate the patient who directly or indirectly help the government by reducing the economical burden to the patient.