Hypertriglyceridemia is a condition in which the triglycerides are raised in the blood and the disease is often seen associated with diabetes mellitus, a disease more common in developed countries. It is one type of dyslipidemia; there are several other types too. Different guidelines around the world define hypertriglyceridemia with reference to the levels of triglycerides in the blood. The diagnosis of hypertriglyceridemia must be taken into special consideration in order to understand the underlying secondary disease i.e. diabetes mellitus if present and its particular type. The lab analysis of serum or plasma is helpful in that case. The disease can be managed on the basis of the extent to which the levels of TG are raised in the body. A review of different approaches to treat the disease is the objective of the article.