Issn  2249-7579
e Issn  2249-7579
Publisher JOURNAL OF PHARMACEUTICAL BIOLOGY

A CASE REPORT ON MALLORY-WEISS SYNDROME

Nikhil M
Department of pharmacy practice, The Dale View College of Pharmacy and Research Centre, Thiruvananthapuram, Kerala, India
Kesiya Simon
Department of pharmacy practice, The Dale View College of Pharmacy and Research Centre, Thiruvananthapuram, Kerala, India
Amina Jabin
Department of pharmacy practice, The Dale View College of Pharmacy and Research Centre, Thiruvananthapuram, Kerala, India
Anjana Sankar
Department of pharmacy practice, The Dale View College of Pharmacy and Research Centre, Thiruvananthapuram, Kerala, India
Sruthy Prasad
Department of pharmacy practice, The Dale View College of Pharmacy and Research Centre, Thiruvananthapuram, Kerala, India
Mohammed Bilal
Department of pharmacy practice, The Dale View College of Pharmacy and Research Centre, Thiruvananthapuram, Kerala, India
Safna N Fazil
Department of pharmacy practice, The Dale View College of Pharmacy and Research Centre, Thiruvananthapuram, Kerala, India

Hematemesis ,Coagulation therapy ,Sclerotherapy ,Blumia ,

Mallory Weiss Syndrome (MWS) is a condition marked by a tear in the mucous membrane, or inner lining, where the esophagus meets the stomach. Most tears heal within 7-10 days without treatment, but MWS can cause significant bleeding. The most common cause of MWS is severe or prolonged vomiting. While this type of vomiting can occur with stomach illness, it also frequently due to chronic alcohol abuse or blumia. In most cases the symptoms will develop as abdominal pain, hematemesis, involuntary retching, bloody or black stool. If the symptoms indicate active bleeding in the esophagus, the doctor will suggest for esophagogastroduodenoscopy (EGD) and the red blood cell count may be low due to bleeding in the esophagus. According to the National Organisation for Rare Disorders, the bleeding that results from tears in the esophagus will stop on its own in about 80-90% of MWS cases. If bleeding continues, sclerotherapy and coagulation therapy are the prefered treatment. In addition some medications can also be used to reduce the stomach acid production such as famotidine or lansoprazole.

9 , 2 , 2019

63 - 64